Transcriptomics analysis and hormonal changes of male and female neonatal rats treated chronically with a low dose of acrylamide in their drinking water
Acrylamide is known to produce follicular cell tumors of the thyroid in rats.RccHan Wistar rats were exposed in utero to a carcinogenic dose of acrylamide (3 mg/Kg bw/day) from gestation day 6 to delivery and then through their drinking water to postnatal day 35.In order to identify potential mechanisms of carcinogenesis in the thyroid glands, we u